Table 2 Relationship between anamorelin responder and baseline characteristics (n = 44)
From: Real-world data of anamorelin in advanced gastrointestinal cancer patients with cancer cachexia
Characteristics | Responder | Non-responder | Odds ratio | p-value* | |
|---|---|---|---|---|---|
(n = 28) | (n = 16) | ||||
Sex | female | 9 (33.3) | 6 (37.5) | 0.79 | 0.48 |
male | 19 (66.7) | 10 (62.5) | |||
Age (year) | < 75 | 22 (78.6) | 7 (43.8) | 4.71 | 0.03 |
≥ 75 | 6 (21.4) | 9 (56.3) | |||
ECOG PS | 0–1 | 21 (75.0) | 14 (87.5) | 0.43 | 0.45 |
≥ 2 | 7 (25.0) | 2 (12.5) | |||
Albumin (g/dL) | ≥ 3.2 | 18 (64.3) | 10 (62.5) | 1.08 | 1.00 |
< 3.2 | 10 (35.7) | 6 (37.5) | |||
CRP (mg/dL) | > 0.5 | 13 (46.4) | 8 (50.0) | 0.87 | 1.00 |
≥ 0.5 | 15 (53.6) | 8 (50.0) | |||
Hemoglobin (g/dL) | ≥ 12.0 | 5 (17.9) | 4 (25.0) | 0.65 | 0.70 |
< 12.0 | 23 (82.1) | 12 (75.0) | |||
Baseline BW loss | 5–10% | 15 (53.6) | 11 (68.8) | 0.52 | 0.36 |
≥ 10% | 13 (46.4) | 5 (31.3) | |||
Tumor type | CRC | 10 (35.7) | 6 (37.5) | 0.20 | |
GC | 10 (35.7) | 3 (18.8) | |||
PC | 8 (28.6) | 7 (43.8) | |||
Disease status | UR-LA | 7 (25.0) | 3 (18.8) | 0.08 | |
Metastatic | 12 (42.9) | 8 (50.0) | |||
Recurrence | 9 (32.1) | 5 (31.3) | |||
No. of previous regimens | 0–1 | 22 (78.6) | 11 (68.8) | 1.67 | 0.49 |
≥ 2 | 6 (21.4) | 5 (31.3) | |||
History of gastric surgery | No | 22 (78.6) | 14 (87.5) | 0.52 | 0.69 |
Yes | 6 (21.4) | 2 (12.5) |