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Table 3 Factors associated with patients with advanced cancer in palliative care during the COVID-19 pandemic

From: Comparison of the sociodemographic and clinical profiles of cancer patients admitted to a tertiary palliative care unit before and during the COVID-19 pandemic

Variables

During the COVID-19 pandemic

Univariate

Multivariate

OR (95% CI)

p-valued

OR (95% CI)

p-valuee

Age ≥ 60 years (ref < 60 years)

0.90 (0.64–1.26)

0.544

-

 

Female (ref. male)

0.95 (0.68–1.33)

0.764

-

 

White skin color (ref: non-white)a

1.74 (1.22–2.47)

0.002

1.66 (1.15–2.39)

0.006

Primary tumor site

    

GI tract (ref: othersc)

3.06 (1.64–5.71)

< 0.001

2.95 (1.55–5.62)

0.001

Gynecological (ref: othersc)

2.13 (1.16–3.92)

0.015

1.63 (0.86–3.09)

0.133

Head and neckb (ref: othersc)

1.64 (0.88–3.08)

0.121

1.18 (0.60–2.32)

0.630

Breast (ref: othersc)

1.33 (0.69–2.57)

0.390

1.17 (0.59–2.34)

0.643

Lung (ref: othersc)

1.58 (0.77–3.23)

0.207

1.49 (0.71–3.13)

0.285

Skin, bones, and soft tissue (ref: othersc)

2.53 (1.22–5.24)

0.013

2.40 (1.13–5.08)

0.023

Distant metastasis (ref: no)

1.38 (0.90–2.13)

0.143

-

 

Prior treatment (ref: no)

1.13 (0.73–1.76)

0.579

-

 

Types of prior treatment (ref: no)

    

Surgery (ref: no)

0.99 (0.71–1.37)

0.946

-

 

Chemotherapy (ref: no)

1.37 (0.96–1.96)

0.079

-

 

Radiotherapy (ref: no)

1.49 (1.07–2.07)

0.018

1.83 (1.26–2.55)

0.001

KPS (%)

1.01 (1.00–1.02)

0.118

-

 

PG-SGA SF (score)

1.05 (1.02–1.07)

0.001

1.06 (1.02–1.09)

0.001

Symptoms

    

Hyporexia (ref: no)

1.55 (1.12–2.16)

0.009

-

 

Nausea (ref: no)

1.50 (1.06–2.12)

0.023

-

 

Vomiting (ref: no)

1.56 (1.06–2.31)

0.025

-

 

Fatigue (ref: no)

1.09 (0.76–1.56)

0.643

-

 

Pain (ref: no)

1.15 (0.81–1.63)

0.422

-

 

Mood-related: depression, anxiety, or sadness (ref: no)

1.25 (0.74–1.35)

0.489

-

 

Time between triage at the institution and 1st assessment at CH IV (days)

1.01 (1.01–1.02)

0.036

-

 

Time between triage at the institution and death (days)

1.00 (0.99–1.00)

0.254

-

 

Time between 1st assessment at CH IV and death (days)

0.99 (0.99–1.00)

0.201

-

 
  1. Note: OR = odds ratio; CI = confidence interval; GI = gastrointestinal; KPS = Karnofsky Performance Status; PG-SGA SF = Patient-Generated Subjective Global Assessment Short Form; CH IV = Cancer Hospital IV
  2. aBrown/mulatto/brunette/indigenous/yellow
  3. bOral and nasal cavity, pharynx, larynx, salivary glands, paranasal sinuses, eyes, and thyroid
  4. c/Leukemia, lymphoma, myeloma, central nervous system, kidney and urinary tract, male genital organs, peritoneum, mediastinum and unrecognized site
  5. dp-value refers to univariate logistic regression
  6. ep-value refers to multiple logistic regression. All variables with p < 0.200 in the univariate analysis were selected for the multivariate logistic regression analysis. Variables with p < 0.050 retained in the final model